MicroGen DX

The second pan-resistant Candidozyma (Candida) auris case has been documented worldwide.¹

What the study found:
• An isolate from Kenya resisted all four major antifungal classes: azoles, echinocandins, polyenes and flucytosine¹
• It came from a hospital-acquired surgical site infection in a 28-year-old patient¹
• Resistance was identified by culture-based susceptibility testing (VITEK 2) and whole-genome sequencing of the cultured isolate¹
• It is the first pan-resistant case reported outside the US; the only earlier case was in New York in 2022¹

Why it matters for infection control:
• C. auris is a WHO high-priority fungal pathogen that persists on surfaces and spreads between patients in healthcare facilities¹ ³
• Fast identification triggers isolation and infection-control measures, and culture-based susceptibility testing guides treatment³
• MicroGenDX identifies bacteria and fungi, with results within ~24 hours from sample receipt²

Read the full study: https://doi.org/10.1038/s41598-026-70653-9

How is your facility approaching C. auris screening today?

Image: AI-generated scientific illustration.



References
1. Odoyo E, Kigen C, Wachira J, et al. Emergence of pan-drug resistant Candidozyma auris in Kenya, the second globally documented case. Sci Rep. 2026. https://doi.org/10.1038/s41598-026-70653-9
2. MicroGenDX data on file.
3. Centers for Disease Control and Prevention. C. auris for Healthcare and Laboratory Professionals. https://www.cdc.gov/candida-auris/hcp/index.html. Accessed October 2026.

What’s seen under the microscope, missed by culture, yet still causes sinus infection? 🔬🧫

Fungal balls. These clumps of fungus grow inside a sinus cavity, and can cause chronic sinus infection symptoms like facial pressure, congestion, and discharge.

To better detect them, researchers studied 45 sinus samples (38 fungal balls) using microscopy, culture, and DNA sequencing.

They found:
🔬 Microscopy spotted fungus in 97.3% of samples but couldn't say which one it was.
🧫 Culture grew fungus in less than a third of samples.
🧬 DNA sequencing identified fungi in every case and even found bacteria living alongside the fungi in some samples!

MicroGenDX's NGS testing goes further, identifying bacteria and fungi at the species level for clearer answers and care.

If you're dealing with chronic sinus issues, consider our SinusKEY testing: https://loom.ly/J8-1BrI

Study: Dellière et al., Journal of Fungi, 2021 (peer-reviewed). https://loom.ly/g6UdkAc

Some lab results can leave you with more questions than answers.

"No growth" means nothing grew under that test's conditions. “Mixed flora" and "normal flora" don't tell you which organism, if any, is behind your symptoms.

MicroGenDX results deliver real insight. They show the bacteria and fungi in your sample, along with:

1️⃣ Name of each organism to the species level
2️⃣ Abundance of each microbe in your sample
3️⃣ Detection of 17 drug resistance genes
4️⃣ List of potential treatment options for your doctor to consider

Our step-by-step guide walks through each section: https://loom.ly/MwCS_iI

Questions? Our Customer Service team can walk you through your report (not medical advice) at 1-855-208-0019.

An infection can involve more than one microbe, and missing one can mean missing part of the picture. SK's experience reflects what comprehensive testing is supposed to deliver: precise microbial detection your provider can rely on.

Our testing is 99.2% accurate, independently verified by the College of American Pathologists (CAP)— more reliable than standard culture testing.

Have you used MicroGenDX testing before?
Share your story with us: https://loom.ly/H7DubtE

Some infections aren't rare. The bacteria behind them are just too picky for a standard petri dish.

Fastidious microbes are real and capable of causing infection, but they only grow with very specific nutrients they can't make themselves. Without those exact conditions like chocolate agar, made by heating blood agar to release trapped nutrients — the plate looks empty, but the microbe is still there.

Standard culture assumes common nutrients, common air, and a few days' time. Fastidious microbes, including Haemophilus, Neisseria gonorrhoeae, Campylobacter, Helicobacter, and Mycoplasma/Ureaplasma, break all three assumptions. A negative result can mean "wrong conditions," not "no infection."

Molecular testing doesn't need a microbe to grow. It identifies over 60,000 microbes with 99.2% accuracy by reading each one's DNA signature.

Get real answers: https://loom.ly/i6FwFxE

Your culture came back negative. Your patient still has endocarditis.

What valve tissue testing finds when culture does not:

• 90.9% vs 39.4%. Molecular detection against valve culture on the same 100 specimens (Berinson 2025, 95% CI 81.3 to 96.6)

• 645 patients, three countries. Johansson 2023 (n=279) and Rodriguez-Garcia 2021 (n=266) found the same gap in independent cohorts

• 71.4% vs 24.1%. The gap after ten or more days of preoperative antibiotics (Rodriguez-Garcia 2021, p = 0.005)

• 12 days. Accuracy was highest for valves resected within 12 days of blood culture negativization (Lazarevic 2025)

• Major Criterion for three organisms only. Bartonella species, Coxiella burnetii, Tropheryma whipplei. Minor Criterion pending further data for everything else (Fowler 2023)

• Blood culture stays first line. It returns phenotypic susceptibility that sequencing does not

At resection, collect one dedicated valve specimen for molecular testing. Do not split a single sample downstream.

About the laboratory:

• 99.2% accuracy, independently validated. CAP-accredited, CLIA-certified, CLEP-permitted (NYS DOH)

• 60,000+ organisms, up to 17 AMR gene targets, ~$400 per test

• Covered by traditional Medicare under PLA code 0112U (Infectious agent detection and identification, targeted sequence analysis (16S and 18S rRNA genes) with drug-resistance gene) and existing Local Coverage Determinations. In cases of insurance denial, patient responsibility is typically $249.

Some infections are caused by bacteria that die the moment air touches them. So how do they still make you sick?

Anaerobic bacteria grow without oxygen and can be destroyed by air exposure in as little as 10 minutes. They live naturally in the mouth, throat, intestine, and skin, but can cause serious infection in a wound, cut, or deep tissue.

Detecting them is a logistics problem. Samples must stay oxygen-free, use specialized media, and incubate for extended periods just to grow. It's harder still because anaerobes rarely act alone, and a culture that grows their aerobic partner can look like the whole story when it’s not.

The data backs this up. In a study of 30 chronic wound patients, researchers tried and failed to culture anaerobes every time, yet molecular testing found they made up 30% of the bacteria in diabetic foot ulcers and 62% in pressure ulcers. Across 80,000 of our own sinus and ear samples, we found anaerobes present in 45% of specimens, and dominant in 12%.

Left overlooked, anaerobic infections can lead to sepsis, organ failure, and even amputation. Accurately identifying the microbe is what unlocks effective treatment.

Molecular testing like NGS skips the oxygen-free handling and days of incubation, reading microbial DNA directly for more accurate answers.

Learn more about NGS: https://loom.ly/kqt3UuI

Sources: Dowd et al., BMC Microbiology, 2008; MicroGenDX qPCR+NGS clinical data, ~80,000 ENT samples

Speed can matter just as much as your answers. With results in as little as 24 hours after your sample reaches the lab, you don't have to wait to start the conversation with your provider. Wendy's results came through quickly so she could take them to her provider, so she had no delay in receiving care.

Get real answers: https://loom.ly/i84-ARI